In summary, GHR (Growth Hormone Releaser) is an amino acid formulation that was designed to stimulate the production of growth hormones in the body. GHR also contains calcium, and colostrum that is rich in growth factors. It is important for parents to help their children to obtain proper nutritious diet, exercise more (or be more active), have a good sleep pattern and maintain a happy mood. GHR is a useful supplement for short children, especially before and during their puberty period.
Alba-Roth J., Müller O.A., Schopohl J., von Werder K., Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion. J Clin Endocrinol Metab. 1988 Dec; 67 (6): 1186-9. Bellone J., Valetto M.R., Aimaretti G., Segni M., Volta C., Cardimale G., Baffoni C., Pasquino A.M., Bernasconi S., Bartolotta E., Mucci M., Ghigo E.,Effects of phenylalanine, histidine, and leucine on basal and GHRH-stimulated GH secretion and on PRL, and glucose levels in short children. Comparison with the effects of arginine. J Pediatr Endocrinol Metab. 1996 Sep-Oct; 9(5): 523-31. Charney D.S., Heninger G.R., Reinhard J.F. Jr., Sternberg D.E., Hafstead KM., The effect of intravenous L-tryptophan on prolactin and growth hormone and mood in healthy subjects. Psychopharmacology (Berl). 1982; 77 (3): 217-22. Evain-Brion D., Donnadieu M., Roger M., Job J.C., Simultaneous study of somatotropic and corticotrophic pituitary secretions during ornithine infusion test, Clin Endocrinol (Oxf), 1982 Aug; 17 (2): 119-22. Gertner J.M., Wajnrajch M.P., Leibel R.L., Genetic defects in the control of growth hormone secretion. Horm Res. 1998; 49 Suppl 1:9-14. GNC Healthnotes: www.gnc.com
Lindgren B.F., Segovia B., Lassarre C., Binoux M., Gourmelen M., Growth retardation in constitutionally short children is related both to low serum levels of i-like growth factor-1 and to its reduced bioavailability, Growth Regul, 1996 Sep; 6 (3): 158-64. Molgaard C., Thomsen B.L., Michaelsen K.F., Effect of habitual dietary calcium intake on calcium supplementation in 12–14-y-old girls, Am J Clin Nutr. 2004 Nov; 80 (5): 1422-7. Wikipedia: http://en.wikipedia.org